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That role makes it a critical part of how mitochondria turn food into ATP, how cells repair DNA, and how a family of regulatory proteins called sirtuins control gene activity

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Potent and selective inhibitors of NAD(+)-dependent 15-hydroxyprostaglandin… [PMID: 21735612] Laboratory literature summary: Potent and selective inhibitors of NAD(+)-dependent 15-hydroxyprostaglandin dehydrogenase (HPGD)